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Then cDNA was synthesized using High-Capacity cDNA Reverse Transcription Kits (4374967, Applied Biosystems) with the accompanied random primers, as described previously ( The mRNA expression levels of given genes in the transfected cells with or without cell sorting enrichment were determined by qPCR using Taq388 mix (Supplementary Table S3

Rather than continuous supplementation, Epitalon aims to stimulate the pineal gland restoration processes that then continue independently for months

8 Center for Public Health Genomics, Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA

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Improves elasticity, reduces wrinkles, and supports collagen regeneration